Drug Standards
Medchemexpress LLC Irinotecan-d10 hydrochloride | 718612-62-5 | 99.76% | 633.20 | 1 MG
Irinotecan-d10 (hydrochloride) is the deuterium labeled Irinotecan. Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled Irinotecan.
- Topoisomerase I inhibitor.
- Prevents religation of the DNA strand by binding to topoisomerase I-DNA complex.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- For research use only.
Medchemexpress LLC Latanoprost acid | 41639-83-2 | 95.1% | 390.51 | 50 MG
Latanoprost acid, an analog of prostaglandin (PG) F2α, is a selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. It inhibits RANKL-induced osteoclastogenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, followed by the c-fos/NFATc1 pathway. Latanoprost acid is a medication used to lower pressure inside the eyes.
- Selective prostanoid receptor (FP) agonist
- Specifically activates the FP-PG receptor
- Inhibits RANKL-induced osteoclastogenesis and function
- Inhibits ERK, AKT, JNK, and p38 cascade
- Inhibits the c-fos/NFATc1 pathway
- Lowers pressure inside the eyes
- Reduces the protein expressions of c-fos and NFATc1 in vitro
- Significantly inhibits mature osteoclast formation in vitro
- Notably prevents LPS-induced bone destruction in vivo
Sigma Aldrich Fine Chemicals Biosciences Doxapram hydrochloride United States Pharmacopeia (USP) Reference Standard | 7081-53-0 | 200MG
Doxapram hydrochloride United States Pharmacopeia (USP) Reference Standard | Mol Wt: 432.98 | 7081-53-0 | 200MG
Sigma Aldrich Fine Chemicals Biosciences Gadodiamide European Pharmacopoeia (EP) Reference Standard | 131410-48-5 |
Gadodiamide European Pharmacopoeia (EP) Reference Standard | Mol Wt: 573.66 | 131410-48-5 |
Medchemexpress LLC Doxazosin mesylate | 77883-43-3 | 98.5% | C24H29N5O8S | 1 ML
Doxazosin mesylate is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. It is the mesylate salt form of doxazosin, a long-lasting inhibitor of α1-adrenoceptors widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms. It may also have a direct inhibitory effect on cholesterol synthesis, potentially leading to upregulation of the LDL receptor and a reduction in LDL cholesterol.
- Selectively antagonizes postsynaptic α1-adrenergic receptors
- Long-lasting inhibitor of α1-adrenoceptors
- Used to treat benign prostatic hyperplasia and lower urinary tract symptoms
- May have a direct inhibitory effect on cholesterol synthesis
Medchemexpress LLC (Rac)-Moxifloxacin | 354812-41-2 | 99.5% | C21H24FN3O4 | 1 MG
(Rac)-Moxifloxacin, also known as (Rac)-BAY 12-8039 free base, is an isoform of Moxifloxacin Hydrochloride. It functions as an oral 8-methoxyquinolone antimicrobial, primarily used in the treatment of various bacterial infections including acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.
- Functions as an oral 8-methoxyquinolone antimicrobial
- Used in treatment of acute bacterial sinusitis
- Used in treatment of acute bacterial exacerbations of chronic bronchitis
- Used in treatment of community-acquired pneumonia
- Rapid action against Listeria monocytogenes
- Demonstrates complete broth sterilization within 24 hours
- Offers protection against macrophage lysis
- Significantly prolonged survival in in vivo studies
- Reduced bacterial overgrowth in spleens and lungs without toxicity
Chromadex Rebaudioside M(P) | 1220616-44-3 | MFCD31916341 | 25mg
Rebaudioside M(P) | Putity: 96.3 | MW: 1291.29 | 1220616-44-3 | MFCD31916341 | 25mg
Medchemexpress LLC (rel)-Tivantinib | 905853-99-8 | 96.5% | C23H19N3O2 | 1 ML
(rel)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. It also targets GSK3α and GSK3β, which are significant in the cellular mechanism of non-small cell lung cancer (NSCLC). This product is intended for research use only.
- Potent and highly selective inhibitor of c-MET
- Targets GSK3α and GSK3β
- Important in the cellular mechanism of non-small cell lung cancer (NSCLC)
- For research use only
Sigma Aldrich Fine Chemicals Biosciences Nalidixic acid >=98% | 389-08-2 | MFCD00006884 | 5G
Nalidixic acid >=98% | Purity: >=98% | Mol Wt: 232.24 | 389-08-2 | MFCD00006884 | 5G
Medchemexpress LLC 2-(4-formylphenyl)propionic acid | 43153-07-7 | MFCD08275588 | C10H10O3 | 10MG
Ibuprofen Impurity K (2-(4-formylphenyl)propionic acid; CAS 43153-07-7) is a known degradation product of ibuprofen used as an analytical reference standard in impurity profiling, stability testing, and method development. It is a racemic aromatic propionic acid (C10H10O3, MW 178.18) typically supplied in milligram quantities for laboratory and quality-control use.
- Used as an analytical reference standard for impurity identification and quantification.
- Applicable to stability testing and forced-degradation studies.
- Suitable for HPLC method development and validation.
- Provided as a racemic form for representative impurity profiling.
- Molecular formula C10H10O3 and molecular weight 178.18 for analytical calculations.
- Available in small quantities suitable for research and quality-control applications.
Medchemexpress LLC Latanoprost lactone diol | 145667-75-0 | MFCD05865275 | 99.9% | 304.38 | C18H24O4 | 50MG
Latanoprost lactone diol is a chemical intermediate and analytical standard used in the synthesis and study of prostaglandin analogs such as latanoprost. Supplied for research use only, it is offered in solid and solution formats for medicinal chemistry and ophthalmic research applications.
- CAS number 145667-75-0.
- Purity 99.86% (reported by supplier).
- Molecular weight 304.38 g/mol.
- Available in multiple sizes, including 50 mg.
- Provided as solid and DMSO solution formats.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC 1β,25-dihydroxyvitamin D3 | 66791-71-7 | 98.0% | C27H44O3 | 10MG
Impurity B of Calcitriol (1β,25-dihydroxyvitamin D3) is an analytical reference standard supplied for laboratory research and analytical applications. It is an identified impurity of calcitriol, the hormonally active metabolite of vitamin D3 that modulates the vitamin D receptor. This material is for research use only and is not intended for human or clinical use.
- High reported purity of 98.0% suitable for analytical assays.
- Provides chemical identity C27H44O3 and molecular weight 416.64 g/mol.
- Offered in multiple small package sizes for analytical workflows.
- Intended specifically for research use only.
- Supplied with a batch-specific certificate of analysis for traceability.
Medchemexpress LLC Methyl linolenate | 301-00-8 | 99.46% | 292.46 | 500 MG
Methyl linolenate is identified as a polyunsaturated fatty acid (PUFA). It exhibits anti-melanogenesis activity with an IC50 of 60 μM. This compound is also valuable for research into the mechanisms and prevention of oxidation and peroxidation of unsaturated fatty acids.
- Functions as a polyunsaturated fatty acid (PUFA).
- Demonstrates anti-melanogenesis activity.
- Useful for studying oxidation/peroxidation mechanisms of unsaturated fatty acids.
- Down-regulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins in B16F10 cells at specific concentrations.
Sigma Aldrich Fine Chemicals Biosciences Lamivudine >=98% (HPLC), powder | 134678-17-4 | MFCD00869739 | 50MG
Lamivudine >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 229.26 | 134678-17-4 | MFCD00869739 | 50MG
Medchemexpress LLC Amoxicillin impurity 1 | 126247-63-0 | MFCD24682762 | 50mg
Amoxicillin Impurity 1 is an impurity of Amoxicillin (HY-B0467A)